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Kuzuoglu-Ozturk, D., Aksoy, O., Schmidt, C., Lea, R., Larson, J.D., Phelps, R.R.L., Nasholm, N., Holt, M., Contreras, A., Huang, M., et al. (2023). N-myc-Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma. Cancer Res. 83, 130–140. 10.1158/0008-5472.CAN-22-0945.
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Hahn, W.C., Bader, J.S., Braun, T.P., Califano, A., Clemons, P.A., Druker, B.J., Ewald, A.J., Fu, H., Jagu, S., Kemp, C.J., Cancer Target Discovery and Development Network, et al. (2021). An expanded universe of cancer targets. Cell 184, 1142–1155. 10.1016/j.cell.2021.02.020.
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Lambo, S., Gröbner, S.N., Rausch, T., Waszak, S.M., Schmidt, C., Gorthi, A., Romero, J.C., Mauermann, M., Brabetz, S., Krausert, S., et al. (2019). The molecular landscape of ETMR at diagnosis and relapse. Nature 576, 274–280. 10.1038/s41586-019-1815-x.
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Sabelström, H., Petri, R., Shchors, K., Jandial, R., Schmidt, C., Sacheva, R., Masic, S., Yuan, E., Fenster, T., Martinez, M., et al. (2019). Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness. Cell Rep. 28, 2064-2079.e11. 10.1016/j.celrep.2019.07.071.
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Ilkhanizadeh, S., Sabelström, H., Miroshnikova, Y.A., Frantz, A., Zhu, W., Idilli, A., Lakins, J.N., Schmidt, C., Quigley, D.A., Fenster, T., et al. (2018). Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma. Mol. Cancer Res. 16, 777–790. 10.1158/1541-7786.MCR-17-0413.
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Schmidt, C.*, Schubert, N.A., Brabetz, S., Mack, N., Schwalm, B., Chan, J.A., Selt, F., Herold-Mende, C., Witt, O., Milde, T., et al. (2017). Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients. Neuro Oncol. 19, 1607–1617. 10.1093/neuonc/nox093.
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Brandenburg, S., Müller, A., Turkowski, K., Radev, Y.T., Rot, S., Schmidt, C., Bungert, A.D., Acker, G., Schorr, A., Hippe, A., et al. (2016). Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors. Acta Neuropathol. 131, 365–378. 10.1007/s00401-015-1529-6.
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Lau, J., Ilkhanizadeh, S., Wang, S., Miroshnikova, Y.A., Salvatierra, N.A., Wong, R.A., Schmidt, C., Weaver, V.M., Weiss, W.A., and Persson, A.I. (2015). STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma. Cancer Res. 75, 4302–4311. 10.1158/0008-5472.CAN-14-3331.
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Moreno, N.*, Schmidt, C.*, Ahlfeld, J., Pöschl, J., Dittmar, S., Pfister, S.M., Kool, M., Kerl, K., and Schüller, U. (2014). Loss of Smarc proteins impairs cerebellar development. J. Neurosci. 34, 13486–13491. 10.1523/JNEUROSCI.2560-14.2014.
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Kool, M., Jones, D.T.W., Jäger, N., Northcott, P.A., Pugh, T.J., Hovestadt, V., Piro, R.M., Esparza, L.A., Markant, S.L., Remke, M., Schmidt, C., et al. (2014). Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell 25, 393–405. 10.1016/j.ccr.2014.02.004.
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Lau, J., Schmidt, C., Markant, S.L., Taylor, M.D., Wechsler-Reya, R.J., and Weiss, W.A. (2012). Matching mice to malignancy: molecular subgroups and models of medulloblastoma. Childs Nerv Syst 28, 521–532. 10.1007/s00381-012-1704-1.